Open-Field
The open field test is a common measure of exploratory behavior and general activity in rodents. When placed in an open and novel space, rodents tend to explore and remain in the areas along the chamber lateral walls for their thigmotaxis. Therefore, the expression of anxiety can be measured by comparing the duration and/or frequencies lingering in the outer and central area. The open field test is useful in studying the motor activity, anxiety and drug effects on the spontaneous locomotion.
The video-tracking (EthoVision XT) is used to measure the traveling distances, cumulative duration, and frequencies into the arena, outer and central area during the experiment.
Arena: S1, S2, S3, S4, S5, S6, S7, S8, S9.
Outer areas: S1, S2, S3, S4, S6, S7, S8, S9.
Central area: S5.
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